9:45 am Myeloid Cells Orchestrate Fibrosis in MASH: A Call to Refocus Therapeutic Targeting Beyond Adaptive Immunity
Time: 9:45 am
day: Combination & Sequential Therapy Focus Day
Details:
- Investigating immune-mediated mechanisms driving fibrosis in MASH, with emphasis on the interplay between innate and adaptive immune cells
- Identifying myeloid cells as essential architects of the fibrotic niche, promoting bystander T-cell accumulation and activating myofibroblasts
- Supporting reorienting anti-fibrotic strategies toward targeting innate immune and stromal components, based on integrated analyses from human and preclinical models
