PATRICE MIMCHE
Seminars
Monday 29th September 2025
12:00 pm EPHB2 Deficiency Suppresses Liver Fibrosis in Metabolic Dysfunction-Associated Steatohepatitis
- Hepatic EPHB2 expression is elevated in human and murine MASH
- Global EPHB2 deletion, including its deficiency in hepatic stellate cells, attenuates fibrosis in MASH
- Targeting EPHB2 with a novel small molecule inhibitor mitigates MASH fibrosis
